Spontaneous ophthalmic artery occlusion in children due to Hyperhomocysteinemia

Virender Sachdeva; Ravi Garg; Avinash Pathengay; Ramesh Kekunnaya

doi:10.4103/0974-620X.159270

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Year : 2015 | Volume : 8 | Issue : 2 | Page : 122-124

Spontaneous ophthalmic artery occlusion in children due to Hyperhomocysteinemia

Virender Sachdeva¹, Ravi Garg¹, Avinash Pathengay², Ramesh Kekunnaya³
¹ Department of Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Nimmagada Prasad Children's Eye Care Centre, GMRV Campus, Visakhapatnam, Andhra Pradesh, India
² Department of Retina and Vitreous Surgery, LV Prasad Eye Institute, GMRV Campus, Visakhapatnam, Andhra Pradesh, India
³ Department of Pediatric Ophthalmology, Strabismus and Neurophthalmology, Jasti V Ramanamma Children's Eye Care Centre, LVPEI, KAR Campus, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Dr. Virender Sachdeva
Department of Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Nimmagada Prasad Children's Eye Care Centre, LV Prasad Eye Institute, GMRV Campus, Visakhapatnam, Andhra Pradesh - 500 034
India

Source of Support: The work was supported by Hyderabad Eye Research Foundation (HERF), Conflict of Interest: None

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DOI: 10.4103/0974-620X.159270

Ophthalmic artery occlusion usually presents as a sudden onset profound decrease in vision in the middle-aged and elderly patients following periocular procedures (retrobulbar injection/glabellar fat injection), embolism from the heart or after prolonged systemic surgery. In this report, we describe three children with spontaneous ophthalmic artery occlusion who presented with unilateral loss of vision and diagnosed elsewhere as optic atrophy whose detailed history and examination were suggestive of ophthalmic artery occlusion. Detailed systemic and laboratory evaluation revealed hyperhomocysteinemia as the only potential risk factor. To the best of our knowledge, this is the first report of the association of hyperhomocysteinemia and spontaneous ophthalmic artery occlusion.

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