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Year : 2022  |  Volume : 15  |  Issue : 3  |  Page : 415-416  

Persistent pupillary membrane masquerading as a foreign body

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India

Date of Submission02-Nov-2021
Date of Acceptance14-Dec-2021
Date of Web Publication02-Nov-2022

Correspondence Address:
Shikha Gupta
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi - 110 029
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ojo.ojo_320_21

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Keywords: Foreign body, iris strands, PPM

How to cite this article:
Gupta S, Mahalingam K, Singh A, Gupta V. Persistent pupillary membrane masquerading as a foreign body. Oman J Ophthalmol 2022;15:415-6

How to cite this URL:
Gupta S, Mahalingam K, Singh A, Gupta V. Persistent pupillary membrane masquerading as a foreign body. Oman J Ophthalmol [serial online] 2022 [cited 2023 Mar 26];15:415-6. Available from: https://www.ojoonline.org/text.asp?2022/15/3/415/360414

An asymptomatic 16-year-old male presented with a complaint of an intraocular whitish lesion in the left eye noticed incidentally for 1 year that appeared to be a foreign body. However, there was no history of past trauma. On examination, his visual acuity was 6/6, intraocular pressures and fundus were normal in both eyes with no evidence of uveitis in either eye. On gross examination, it appeared to be an opaque foreign body over the left inferior iris [Figure 1]a. On higher magnification on slit-lamp biomicroscopy, it was seen attached to thick iris strands arising from collarette [[Figure 1]b; arrow] and showed dynamicity on ocular movements. On high-resolution anterior segment optical coherence tomography (Spectralis, Heidelberg, Germany), it was confirmed to be attached to the iris strands arising from the iris stroma and was partially cystic [Figure 1]c. Due to these characteristics, the lesion was finally diagnosed as regressed “persistent pupillary membrane,” and the patient was advised against intervention. Classically described as thin white cobweb-like strands over the pupil, it is composed of fibrovascular tissue.[1],[2] Failure of involution of primitive hyaloid vasculature may result in its persistence, which is usually innocuous.[3],[4] Although cysts arising from the pigmented iris epithelium have been shown to wobble with ocular movements and have also been shown to be free-floating sometimes, demonstration of dynamicity on ocular movement [Video 1 [Additional file 1]] in this type of persistent membrane has not been described before.[5]
Figure 1: (a) slit-lamp clinical picture showing foreign body-like structure (white fibrotic lesion) in the anterior chamber, attached to iris strands (b, white arrow) arising from the collerette. Furthermore, the white fibrotic lesion had dispersed brown pigmentation akin to that of the iris, suggesting a common origin. (c) Anterior segment optical coherence tomography confirming its attachment to the iris strands arising from the iris stroma (white arrow)

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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his images and other clinical information to be reported in the journal. The patient understands that his name and initials will not be published and due efforts will be made to conceal identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.

   References Top

Matsuo N, Smelser GK. Electron microscopic studies on the pupillary membrane: The fine structure of the white strands of the disappearing stage of this membrane. Invest Ophthalmol 1971;10:108-19.  Back to cited text no. 1
Lambert SR, Buckley EG, Lenhart P, Zhang Q, Grossniklaus HE. Congenital fibrovascular pupillary membranes: Clinical and histopathological findings. Ophthalmology 2012;119:634-41.  Back to cited text no. 2
Yadav M, Mahalingam K, Gupta V. Aniridia with persistent pupillary membrane. Ophthalmol Glaucoma 2021;4:208.  Back to cited text no. 3
Kraus CL, Lueder GT. Clinical characteristics and surgical approach to visually significant persistent pupillary membranes. J AAPOS 2014;18:596-9.  Back to cited text no. 4
Rotsos T, Bagikos G, Christou S, Symeonidis C, Papadaki T, Papaeuthimiou I, et al. Free-floating iris pigmented epithelial cyst in the anterior chamber. Case Rep Ophthalmol Med 2016;2016:4731037.  Back to cited text no. 5


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