Oman Journal of Ophthalmology

REVIEW ARTICLE
Year
: 2015  |  Volume : 8  |  Issue : 2  |  Page : 83--85

Recent trends: Medical management of infectious keratitis


Sneha Solanki, Manisha Rathi, Sumeet Khanduja, CS Dhull, Sumit Sachdeva, Jitender Phogat 
 Department of Ophthalmology, Regional Institute of Ophthalmology, Pt.B.D. Sharma, PGIMS, Rohtak, Haryana, India

Correspondence Address:
Dr. Sneha Solanki
C-103, Hextex Commune, Sector-43, Gurgaon, Haryana
India

This review article highlights the newer diagnostic modalities and approaches in the medical management of infectious keratitis. A Medline literature search conducted to March 2014 has been included. Recent studies or publications were selected from international indexed journals using suitable key words. Development of specular microscopy and polymerase chain reaction (PCR) has a promising role as diagnostic modalities in infectious keratitis, especially in refractory cases. Previously fortified antibiotics have been the mainstay of treatment for bacterial keratitis. Recently, the advent of fourth-generation fluoroquinolones monotherapy has shown promising results in the management of bacterial keratitis. Corneal collagen cross-linking is being considered in the refractory cases. Topical natamycin and amphotericin B should be considered as the first choice anti-fungal agents in suspected filamentous or yeast infection respectively. Voriconazole and newer routes of administration such as intrastromal and intracameral injection of conventional anti-fungal agents have demonstrated a positive clinical response. Ganciclovir is a newer anti-viral agent with promising results in herpes simplex keratitis. Thus, introduction of newer diagnostic modalities and collagen cross-linking along with fourth-generation fluoroquinolones and newer azoles have a promising role in the management of infectious keratitis.


How to cite this article:
Solanki S, Rathi M, Khanduja S, Dhull C S, Sachdeva S, Phogat J. Recent trends: Medical management of infectious keratitis.Oman J Ophthalmol 2015;8:83-85


How to cite this URL:
Solanki S, Rathi M, Khanduja S, Dhull C S, Sachdeva S, Phogat J. Recent trends: Medical management of infectious keratitis. Oman J Ophthalmol [serial online] 2015 [cited 2023 Feb 5 ];8:83-85
Available from: https://www.ojoonline.org/article.asp?issn=0974-620X;year=2015;volume=8;issue=2;spage=83;epage=85;aulast=Solanki;type=0