Oman Journal of Ophthalmology

CASE REPORT
Year
: 2019  |  Volume : 12  |  Issue : 1  |  Page : 53--54

Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection


Ashok Sharma, Simar Rajan Singh, Mohit Dogra, Chintan Singh, Ramandeep Singh 
 Department of Ophthalmology, Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Dr. Ramandeep Singh
Department of Ophthalmology, Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh
India

We report a case of recurrence of herpes simplex virus (HSV) keratouveitis following the intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO) in a previously adequately treated patient of herpetic keratouveitis. A 47-year-old man with the previous history of HSV keratouveitis was administered 2 doses of intravitreal bevacizumab in the right eye for CRVO, at an interval of 4 weeks. Following the second dose, the patient developed decreased vision, corneal edema, and anterior segment inflammation. Since he was a previously known case of HSV keratouveitis with a positive polymerase chain reaction for HSV from the aqueous, oral valacyclovir was started along with topical steroids and cycloplegics. He showed a good response to treatment with resolution of keratouveitis. This case demonstrates that the recurrence of herpetic keratouveitis can be a possible complication of intravitreal bevacizumab, which may occur even after prior uneventful injections.


How to cite this article:
Sharma A, Singh SR, Dogra M, Singh C, Singh R. Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection.Oman J Ophthalmol 2019;12:53-54


How to cite this URL:
Sharma A, Singh SR, Dogra M, Singh C, Singh R. Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection. Oman J Ophthalmol [serial online] 2019 [cited 2022 Nov 29 ];12:53-54
Available from: https://www.ojoonline.org/article.asp?issn=0974-620X;year=2019;volume=12;issue=1;spage=53;epage=54;aulast=Sharma;type=0